"Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues" (Abelin, J. G., et. al., Nat. Commun. 2023)

Heatmap


Experiment


Getting started

Enter your gene names of interest (official gene symbols, e.g. EGFR) into the text field. You can enter up to 20 genes.


Dataset

The heatmap depicts multi-ome data from the MONTE workflow ("hlaft") and the serial multi-omic enrichment workflow ("noip"). CNA and RNAseq are copied from the LUAD 2020 discovery dataset. HLA tracks show whether at least one class 1 or class 2 peptide was detected in the MONTE workflow. For other data types the heatmap depicts abundances observed in tumor relative to normal adjacent tissue (NAT).

Type# MONTE # serial emrichment # samples
Protein 101580 104630 10
Phosphosites 221580 263920 10
Acetylsites 54350 38600 10
Ubiquitylsites 93950 94790 10

HLA Table


Getting started

Enter your gene name of interest (official gene symbols, e.g. PIK3CA) to view associated HLA-I and HLA-II sequences. Hover over participant names to view HLA-I types, or click the checkbox "show HLA-I typing" to view as a table.



Download HLA tables to see more information, including HLA typing and HLAthena predictions.


HLA-I Typing

HLA-I Sequences

HLA-II Sequences